| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Framber Valdez
| SP | 185 | 13 | 10 | 3.48 | 1.22 | 173 | 61 |
| |
| 2 |
Casey Mize
| SP | 146 | 9 | 9 | 4.11 | 1.25 | 127 | 39 |
| 3 |
Tarik Skubal
| SP | 188 | 14 | 7 | 2.71 | 0.97 | 228 | 38 |
| 4 |
Troy Melton
| SP | 50 | 3 | 3 | 3.90 | 1.23 | 45 | 16 |
| 5 |
Keider Montero
| SP | 50 | 3 | 3 | 4.49 | 1.34 | 42 | 17 |
| 6 |
Jack Flaherty
IL-15
| SP | 159 | 10 | 10 | 4.04 | 1.24 | 175 | 55 |
| 7 |
Justin Verlander
IL-60
| SP | 131 | 7 | 8 | 4.40 | 1.29 | 110 | 42 |