| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Dylan Cease
| SP | 178 | 12 | 9 | 3.53 | 1.20 | 209 | 65 |
| |
| 2 |
Patrick Corbin
| SP | 63 | 4 | 4 | 4.55 | 1.37 | 50 | 20 |
| 3 |
Kevin Gausman
| SP | 185 | 11 | 10 | 3.97 | 1.24 | 181 | 55 |
| 4 |
Max Scherzer
| SP | 117 | 7 | 7 | 4.21 | 1.20 | 117 | 31 |
| 5 |
Eric Lauer
| SP | 66 | 3 | 3 | 4.07 | 1.25 | 63 | 20 |
| 6 |
Cody Ponce
IL-60
| SP | 155 | 9 | 9 | 3.90 | 1.24 | 151 | 44 |