| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Chris Bassitt
| SP | 179 | 11 | 11 | 4.13 | 1.30 | 164 | 61 |
| |
| 2 |
Kevin Gausman
| SP | 193 | 12 | 11 | 3.91 | 1.22 | 192 | 55 |
| 3 |
Easton Lucas
| SP | 24 | 1 | 1 | 4.18 | 1.36 | 21 | 10 |
| 4 |
Jose Berrios
| SP | 191 | 11 | 12 | 4.30 | 1.29 | 166 | 54 |
| 5 |
Bowden Francis
| SP | 159 | 9 | 10 | 4.33 | 1.24 | 147 | 44 |
| 6 |
Max Scherzer
IL-15
| SP | 124 | 8 | 7 | 3.90 | 1.15 | 131 | 31 |
| 7 |
Alek Manoah
IL-60
| SP | 17 | 1 | 1 | 4.11 | 1.28 | 17 | 6 |