| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Roki Sasaki
| SP | 107 | 6 | 5 | 4.17 | 1.31 | 102 | 43 |
| |
| 2 |
Emmet Sheehan
| SP | 134 | 9 | 6 | 3.91 | 1.15 | 152 | 43 |
| 3 |
Yoshinobu Yamamoto
| SP | 161 | 12 | 7 | 3.24 | 1.11 | 175 | 47 |
| 4 |
Shohei Ohtani
| SP | 113 | 8 | 5 | 3.36 | 1.10 | 134 | 35 |
| 5 |
Justin Wrobleski
| SP | 53 | 3 | 3 | 4.29 | 1.28 | 48 | 18 |
| 6 |
Eric Lauer
| SP | 65 | 4 | 4 | 4.23 | 1.27 | 63 | 21 |
| 7 |
Blake Snell
IL-60
| SP | 122 | 9 | 6 | 3.44 | 1.20 | 150 | 52 |
| 8 |
Tyler Glasnow
IL-60
| SP | 129 | 8 | 6 | 3.68 | 1.17 | 151 | 48 |