| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Jose Soriano
| SP | 171 | 10 | 10 | 3.76 | 1.32 | 159 | 73 |
| |
| 2 |
Dylan Cease
| SP | 169 | 11 | 9 | 3.70 | 1.21 | 200 | 64 |
| 3 |
Shane Bieber
| SP | 93 | 6 | 5 | 3.71 | 1.17 | 87 | 22 |
| 4 |
Max Scherzer
| SP | 91 | 6 | 6 | 4.57 | 1.23 | 88 | 24 |
| 5 |
Jameson Taillon
IL-15
| SP | 146 | 10 | 9 | 4.38 | 1.23 | 113 | 34 |
| 6 |
Trey Yesavage
IL-15
| SP | 108 | 7 | 5 | 3.82 | 1.24 | 121 | 45 |
| 7 |
Spencer Arrighetti
| SP | 93 | 5 | 7 | 4.59 | 1.35 | 92 | 40 |
| 8 |
Patrick Corbin
IL-60
| SP | 69 | 4 | 5 | 4.88 | 1.40 | 55 | 23 |
| 9 |
Cody Ponce
IL-60
| SP | 137 | 8 | 8 | 4.05 | 1.25 | 139 | 44 |