| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Framber Valdez
| SP | 188 | 13 | 9 | 3.54 | 1.24 | 174 | 63 |
| |
| 2 |
Troy Melton
| SP | 51 | 3 | 2 | 4.06 | 1.25 | 46 | 16 |
| 3 |
Tarik Skubal
| SP | 192 | 14 | 7 | 2.67 | 0.97 | 234 | 39 |
| 4 |
Casey Mize
| SP | 145 | 9 | 9 | 4.16 | 1.26 | 126 | 40 |
| 5 |
Jack Flaherty
| SP | 159 | 10 | 10 | 4.02 | 1.25 | 175 | 55 |
| 6 |
Keider Montero
| SP | 53 | 3 | 3 | 4.42 | 1.34 | 44 | 18 |
| 7 |
Justin Verlander
IL-60
| SP | 134 | 7 | 8 | 4.57 | 1.31 | 112 | 45 |