| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Chris Bassitt
| SP | 75 | 5 | 4 | 4.60 | 1.31 | 65 | 25 |
| |
| 2 |
Jose Berrios
| SP | 69 | 4 | 5 | 5.01 | 1.35 | 54 | 21 |
| 3 |
Kevin Gausman
| SP | 76 | 5 | 5 | 4.75 | 1.30 | 72 | 24 |
| 4 |
Max Scherzer
| SP | 60 | 4 | 4 | 4.41 | 1.18 | 63 | 18 |
| 5 |
Bowden Francis
IL-15
| SP | 31 | 2 | 2 | 5.14 | 1.30 | 26 | 10 |
| 6 |
Easton Lucas
| SP | 7 | 0 | 0 | 4.54 | 1.35 | 7 | 3 |
| 7 |
Alek Manoah
IL-60
| SP | 14 | 1 | 1 | 4.80 | 1.35 | 12 | 6 |