| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Charlie Morton
| SP | 144 | 10 | 7 | 4.14 | 1.32 | 157 | 61 |
| |
| 2 |
Chris Sale
| SP | 131 | 9 | 7 | 3.81 | 1.15 | 155 | 38 |
| 3 |
Reynaldo Lopez
| SP | 100 | 7 | 5 | 3.98 | 1.25 | 109 | 37 |
| 4 |
Max Fried
| SP | 160 | 13 | 6 | 3.41 | 1.18 | 154 | 39 |
| 5 |
Bryce Elder
| SP | 87 | 5 | 4 | 4.39 | 1.36 | 68 | 32 |
| 6 |
Darius Vines
| SP | 26 | 1 | 1 | 4.37 | 1.30 | 22 | 8 |
| 7 |
Allan Winans
| SP | 16 | 1 | 1 | 4.27 | 1.29 | 15 | 4 |