| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Dylan Cease
| SP | 169 | 11 | 8 | 3.60 | 1.20 | 197 | 65 |
| |
| 2 |
Kevin Gausman
| SP | 178 | 12 | 10 | 3.77 | 1.22 | 174 | 51 |
| 3 |
Max Scherzer
| SP | 109 | 6 | 6 | 4.15 | 1.20 | 104 | 31 |
| 4 |
Eric Lauer
| SP | 66 | 4 | 4 | 4.30 | 1.29 | 59 | 22 |
| 5 |
Patrick Corbin
| SP | 59 | 3 | 4 | 5.19 | 1.47 | 48 | 21 |
| 6 |
Cody Ponce
IL-60
| SP | 153 | 8 | 8 | 4.17 | 1.22 | 149 | 47 |