| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Bryce Elder
| SP | 106 | 8 | 6 | 4.50 | 1.34 | 78 | 36 |
| |
| 2 |
Charlie Morton
| SP | 149 | 10 | 7 | 4.32 | 1.34 | 162 | 65 |
| 3 |
Chris Sale
| SP | 127 | 10 | 6 | 3.59 | 1.14 | 156 | 39 |
| 4 |
Reynaldo Lopez
| SP | 103 | 8 | 6 | 4.05 | 1.23 | 110 | 35 |
| 5 |
Max Fried
| SP | 146 | 12 | 6 | 3.36 | 1.15 | 131 | 36 |
| 6 |
Darius Vines
| SP | 48 | 3 | 2 | 4.35 | 1.26 | 41 | 15 |
| 7 |
Allan Winans
| SP | 12 | 1 | 0 | 3.71 | 1.20 | 11 | 4 |