| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Charlie Morton
| SP | 146 | 10 | 7 | 4.34 | 1.33 | 166 | 64 |
| |
| 2 |
Bryce Elder
| SP | 89 | 6 | 5 | 4.50 | 1.33 | 68 | 30 |
| |
| 3 |
Chris Sale
| SP | 127 | 9 | 7 | 3.74 | 1.15 | 157 | 40 |
| 4 |
Reynaldo Lopez
| SP | 99 | 6 | 5 | 4.20 | 1.23 | 106 | 33 |
| 5 |
Max Fried
| SP | 151 | 12 | 7 | 3.28 | 1.11 | 150 | 35 |
| 6 |
Darius Vines
| SP | 26 | 1 | 1 | 4.17 | 1.24 | 24 | 8 |
| 7 |
Allan Winans
| SP | 16 | 1 | 0 | 3.86 | 1.21 | 15 | 5 |