| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Chris Bassitt
| SP | 170 | 10 | 10 | 4.13 | 1.30 | 157 | 59 |
| |
| 2 |
Kevin Gausman
| SP | 183 | 11 | 11 | 4.00 | 1.24 | 180 | 53 |
| 3 |
Easton Lucas
| SP | 63 | 3 | 4 | 4.42 | 1.40 | 53 | 27 |
| 4 |
Jose Berrios
| SP | 181 | 10 | 11 | 4.30 | 1.29 | 160 | 52 |
| 5 |
Bowden Francis
| SP | 156 | 9 | 10 | 4.36 | 1.25 | 144 | 45 |
| 6 |
Max Scherzer
IL-15
| SP | 108 | 7 | 6 | 3.97 | 1.16 | 114 | 27 |
| 7 |
Alek Manoah
IL-60
| SP | 25 | 1 | 1 | 4.26 | 1.31 | 24 | 9 |